SARMs (Selective Androgen Receptor Modulators) have garnered significant attention for their promising muscular benefits and accessibility. Thanks to their legal status for experimental purposes, sourcing SARMs has become relatively straightforward, making them a popular choice among bodybuilders and fitness enthusiasts.
SARMs are engineered to minimize the adverse effects commonly associated with anabolic steroids through tissue selectivity. This mechanism involves targeting specific androgen receptors, aiming to stimulate those that promote muscle growth while avoiding receptors that lead to undesirable side effects. Consequently, SARMs offer a compelling alternative to traditional steroids, delivering similar benefits with potentially fewer risks.
Both RAD 150 and RAD 140 exemplify the potential of SARMs in bodybuilding. However, understanding their distinct properties and effects is crucial for making an informed decision on which compound to incorporate into your regimen.
Before we jump on to the research, I just wanted to give you a quick brief of the SARMs benefits:
- Muscle Mass: SARMs promote lean muscle growth, contributing to a more sculpted and muscular physique.
- Muscular Strength: Users often experience significant gains in strength, allowing for improved performance in the gym.
- Fat Loss: These compounds can aid in reducing body fat, helping athletes achieve a leaner body composition.
- Endurance: Enhanced stamina and endurance are notable benefits, enabling longer and more intense training sessions.
What the Research Says: RAD 140 Studies
- Monkey Studies
A key study on monkeys demonstrated a 10% increase in lean mass with a RAD 140 dosage of 0.1 mg/kg per day over a 28-day period. For a human weighing 75 kg, this would be equivalent to a daily dose of approximately 7.5 mg. Notably, dosages above 0.1 mg/kg did not yield additional increases in mass, indicating a threshold beyond which higher doses do not enhance muscle growth further.
Importantly, this study also revealed that liver enzyme levels and prostate mass remained stable, suggesting a favourable safety profile for RAD 140 at this dosage.
- Rat Studies
Additional research conducted on rats showed that a RAD 140 dose of 3 mg/kg per day produced muscle gains comparable to a 1 mg/kg dose of testosterone. This finding provides a compelling explanation for why high doses of RAD 140 may rival the muscle-building effects of anabolic steroids. However, it's crucial to consider that 3 mg/kg per day in humans would constitute a megadose, likely accompanied by severe side effects.
Furthermore, there is evidence to suggest that excessively high doses of RAD 140 can be detrimental. Rats at risk of sarcopenia exhibited a higher mortality rate when administered 5 mg/kg per day of RAD 140, indicating that extreme dosages can lead to muscle atrophy and other adverse effects.
Conclusion
The research on RAD 140 underscores its potential as a powerful muscle-building agent with a relatively favourable safety profile at moderate doses. However, it is clear that there is a threshold beyond which the benefits plateau and the risks increase significantly. As with any performance-enhancing substance, careful consideration of dosage and individual response is essential to maximize benefits and minimize risks.
By understanding these studies, bodybuilders can make more informed decisions about incorporating RAD 140 into their regimens, optimizing their gains while prioritizing their health.
So what is Rad 150?
RAD 150, also known as TLB-150, is an esterified version of RAD 140, developed to provide a longer half-life and potentially enhanced anabolic effects. As a new player, RAD 150 has generated interest for its potential to build muscle and improve athletic performance with a potentially improved pharmacokinetic profile. One could say that it is increasing in popularity when looking for bulking steroids.
While specific studies on RAD 150 are still emerging, its development is based on the promising results observed with RAD 140. Here is a summary of what current research and theoretical benefits suggest:
- Extended Half-Life: The primary difference between RAD 150 and its predecessor, RAD 140, is the extended half-life. This means RAD 150 could remain active in the system longer, potentially requiring less frequent dosing and maintaining more consistent effects over time.
- Potential for Enhanced Anabolism: Theoretically, the longer half-life of RAD 150 could enhance its anabolic effects by providing a more sustained stimulus to muscle and bone androgen receptors. This could lead to greater muscle growth and strength gains over prolonged use.
- Safety and Side Effects: Early indications suggest that RAD 150, like RAD 140, may maintain a favourable safety profile with fewer androgenic side effects compared to traditional anabolic steroids. However, as with all SARMs, long-term safety data are still needed, and users should approach with caution.
The Need for More Research
Although RAD 150 shows promise, comprehensive studies, particularly clinical trials on humans, are still required to fully understand its efficacy and safety. Most current knowledge is extrapolated from its molecular similarities to RAD 140 and theoretical benefits due to its esterification.
Rad 140 VS 150 Dosage
The typical recommendation by SARM companies is to use a lower dose of Rad 150 than Rad 140 due to 150 being more potent.
- Rad 150: 10mg/day for 8 weeks
- Rad 140: 15mg/ day for 8 weeks
Cost
Again, due to its potency you'll find Rad 150 slightly more expensive than 140. Below is the most typical pricing model by the best and most reliable SARMs companies:
- RAD 140: $64.99 (15 mg/ml) – 30 ml
- RAD 150: $69.99 (10 mg/ml) – 30 ml
Which Are The Besy SARMs Companies?
I'd say that there are two reliable companies that come up on top of my mind: Swiss Cherms and Sports Technology Labs. Their products are 98-99% pure and come with certificates of independent analysis.
RAD 150 vs RAD 140, Who Wins?
Based on our research, I'd say RAD 140 is the better one due to the amount of research been done on it. RAD 150 is still a bit too risky for my taste. Then again, one can stick to being natural and grow anyway – like these natural bodybuilders.
